The human long noncoding RNAs CoroMarker, MALAT1, CDR1as, and LINC00460 in whole blood of individuals after controlled short-term exposure with ultrafine metal fume particles at workplace conditions, and in human macrophages in vitro

The human long noncoding RNAs CoroMarker, MALAT1, CDR1as, and LINC00460 in whole blood of individuals after controlled short-term exposure with ultrafine metal fume particles at workplace conditions, and in human macrophages in vitro

Abstract Background Short-term inhalation of occupationally relevant ultrafine zinc/copper (Zn/Cu) containing welding fumes has been shown to induce subclinical systemic inflammation, associated with an elevated risk for cardiovascular diseases. The involvement of noncoding RNAs (lncRNAs) in this se...

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Bibliographic Details
Main Authors: Theresa Scheurer, Jan Steffens, Agnieszka Markert, Miriam Du Marchie Sarvaas, Christoph Roderburg, Lothar Rink, Frank Tacke, Tom Luedde, Thomas Kraus, Ralf Baumann
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Journal of Occupational Medicine and Toxicology
Subjects:
LncRNA
Occupational health
Zinc/copper (Zn/cu) metal fume exposure
Nanotoxicology
Macrophages
Online Access:https://doi.org/10.1186/s12995-022-00356-0
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