Obstructive hypertrophic cardiomyopathy: from genetic insights to a multimodal therapeutic approach with mavacamten, aficamten, and beyond

Obstructive hypertrophic cardiomyopathy: from genetic insights to a multimodal therapeutic approach with mavacamten, aficamten, and beyond

Abstract Background A cardiac condition marked by excessive growth of heart muscle cells, hypertrophic cardiomyopathy (HCM) is a complex genetic disorder characterized by left ventricular hypertrophy, microvascular ischemia, myocardial fibrosis, and diastolic dysfunction. Obstructive hypertrophic ca...

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Bibliographic Details
Main Authors: Khadija Sarwer, Saeeda Lashari, Nida Rafaqat, Maher, Abdul Raheem, Muneeb Ur Rehman, Syed Muhammad Iraj Abbas
Format: Article
Language:English
Published: SpringerOpen 2024-12-01
Series:The Egyptian Heart Journal
Subjects:
HCM
oHCM
Mavacamten
Aficamten
Genetic mutations
Myosin inhibitors
Online Access:https://doi.org/10.1186/s43044-024-00587-y
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https://doi.org/10.1186/s43044-024-00587-y

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