The expression profile of inflammatory microRNAs in Leishmania major infected human macrophages; mining the effects of Leishmania RNA virus

The expression profile of inflammatory microRNAs in Leishmania major infected human macrophages; mining the effects of Leishmania RNA virus

Abstract Background Leishmaniasis is a disease caused by the Leishmania parasite. Recent studies suggest a critical role for double-stranded RNA virus (LRV) in the disease outcome. MicroRNAs (miRs) are small, non-coding RNA molecules that may also contribute to the outcome of infection and the patte...

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Main Authors: Zahra Mirabedini, Mehdi Mohebali, Hamed Mirjalali, Homa Hajjaran, Fatemeh Goudarzi, Hanieh Mohammad Rahimi
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Microbiology
Subjects:
Leishmania major
Leishmania RNA virus 2
miR-155
miR-146b
miR-133a
THP-1
Online Access:https://doi.org/10.1186/s12866-025-03901-z
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https://doi.org/10.1186/s12866-025-03901-z

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