Fluoroquinolones for the Prophylaxis of Spontaneous Bacterial Peritonitis in Patients with Liver Cirrhosis: Are They Losing Ground?

Fluoroquinolones for the Prophylaxis of Spontaneous Bacterial Peritonitis in Patients with Liver Cirrhosis: Are They Losing Ground?

Spontaneous bacterial peritonitis (SBP) is the most common bacterial infection in cirrhotic patients. Historically, the bacterial spectrum was dominated by Gram-negative bacteria. However, recent studies showed that fluoroquinolone (FQ)-based prophylaxis promotes the intestinal overgrowth of Gram-po...

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Bibliographic Details
Main Authors: Simona Juncu, Horia Minea, Andreea Lungu, Alina Jucan, Raluca Avram, Ana-Maria Buzuleac, Camelia Cojocariu, Laura Sorina Diaconu, Carol Stanciu, Anca Trifan, Ana-Maria Sîngeap
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Life
Subjects:
spontaneous bacterial peritonitis
prophylaxis
fluoroquinolones
multidrug-resistant organisms
norfloxacin
rifaximin
Online Access:https://www.mdpi.com/2075-1729/15/4/586
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