Ethanol with thioacetamide murine model of alcoholic liver disease identifies hepatic pathways as targets for the human disease

Ethanol with thioacetamide murine model of alcoholic liver disease identifies hepatic pathways as targets for the human disease

Introduction and Objectives: Hepatic proteome and gut microbiota alterations are known in alcohol-associated hepatitis (AAH). Current animal models sparsely mimic human AAH. We aimed to develop an murine model that closely resembled human AAH. Materials and Methods: Male C57BL/6N mice were pair-fed...

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Main Authors: Ashi Mittal, Nishu Choudhary, Sudrishti Chaudhary, Anupama Kumari, Archana Rastogi, Guresh Kumar, Jaswinder Singh Maras, Shiv K Sarin, Shvetank Sharma
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Annals of Hepatology
Subjects:
Alcoholic associated hepatitis
Mice model
Liver fibrosis
Hepatic proteome
Gut microbiome
Online Access:http://www.sciencedirect.com/science/article/pii/S166526812400348X
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