HMGCS2 and AMACR as potential targets linking mitochondrial dysfunction and ulcerative colitis

HMGCS2 and AMACR as potential targets linking mitochondrial dysfunction and ulcerative colitis

Abstract Ulcerative colitis (UC) is characterised notably by an imbalance in intestinal mucosal homeostasis. Although mitochondrial dysfunction has been identified as a potential contributor to this imbalance, it remains an incomplete understanding. Consequently, further investigation into the role...

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Bibliographic Details
Main Authors: Rui Zhu, Xinyu Bai, Zhangqin Li, Hao Liang, Huixian Song, Lifang Chen, Yinglei Miao, Fengrui Zhang, Junkun Niu
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Scientific Reports
Subjects:
Ulcerative colitis
Mitochondria
WGCNA
Machine learning
Immune infiltration
Online Access:https://doi.org/10.1038/s41598-024-82900-y
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https://doi.org/10.1038/s41598-024-82900-y

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