Advances in synaptic PET imaging and intervention with synapse-targeted small-molecular drugs for dementia diagnosis and therapy

Dementia is characterized by synaptic and neuronal dysfunction in disease-specific brain regions. Repeated failure of dementia clinical trials with therapeutic drugs targeting abnormal protein aggregates has caused researchers to shift their focus to synaptic functions and increased the importance o...

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Bibliographic Details
Main Authors: Xiuhong Lu, Bin Ji, Gang Huang, Hong Ding
Format: Article
Language:English
Published: KeAi Communications Co. Ltd. 2025-01-01
Series:Fundamental Research
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Online Access:http://www.sciencedirect.com/science/article/pii/S2667325824001596
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