Stress generation, relaxation and size control in confined tumor growth.

Experiments on tumor spheroids have shown that compressive stress from their environment can reversibly decrease tumor expansion rates and final sizes. Stress release experiments show that nonuniform anisotropic elastic stresses can be distributed throughout. The elastic stresses are maintained by s...

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Bibliographic Details
Main Authors: Huaming Yan, Daniel Ramirez-Guerrero, John Lowengrub, Min Wu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-12-01
Series:PLoS Computational Biology
Online Access:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1009701&type=printable
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