Mechanistic insights into endosomal escape by sodium oleate-modified liposomes

Mechanistic insights into endosomal escape by sodium oleate-modified liposomes

Endosomal entrapment significantly limits the efficacy of drug delivery systems. This study investigates sodium oleate-modified liposomes (SO-Lipo) as an innovative strategy to enhance endosomal escape and improve cytosolic delivery in 4T1 triple-negative breast cancer cells. We aimed to elucidate t...

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Bibliographic Details
Main Authors: Ebrahim Sadaqa, Satrialdi, Fransiska Kurniawan, Diky Mudhakir
Format: Article
Language:English
Published: Beilstein-Institut 2024-12-01
Series:Beilstein Journal of Nanotechnology
Subjects:
aurein 1.2
endosomal escape
fusogenic effect
molecular dynamics simulation
sodium oleate
Online Access:https://doi.org/10.3762/bjnano.15.131
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https://doi.org/10.3762/bjnano.15.131

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