Association of Fontan Pathophysiology With Plasma Bile Acids

Association of Fontan Pathophysiology With Plasma Bile Acids

Background: Patients with Fontan circulation are frail and experience multisystem dysfunction including impaired exercise capacity, low resting and exercise-augmented cardiac output, and progressive liver fibrosis. However, common underlying biochemical abnormalities or disease-specific biomarkers h...

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Main Authors: Ashish H. Shah, MD, MD-Research, Arun Surendran, MSc, Pedram Hassan-Tash, BSc, MD, C. Nolan Turnbull, BSc, Nicole Johnston, MSc, David Goodlett, BSc, PhD, Jun Han, PhD, Robin A. Ducas, MD, James W. Tam, MD, Eberhard Renner, MD, Todd A. Duhamel, PhD, Michel Aliani, MSc, PhD, Amir Ravandi, MD, PhD, Richard A. Krasuski, MD
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:JACC: Advances
Subjects:
bile acids
Fontan circulation
metabolomics
pathophysiology
Online Access:http://www.sciencedirect.com/science/article/pii/S2772963X24008445
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