Phosphodegrons in Health and Disease: From Cellular Homeostasis to Therapeutic Potential

Phosphodegrons are critical motifs that play a pivotal role in the regulation of protein stability and function via phosphorylation-dependent signaling pathways. These motifs serve as recognition elements for ubiquitin ligases, facilitating the targeted degradation of proteins. By modulating key cel...

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Bibliographic Details
Main Authors: Tadashi Nakagawa, Makiko Nakagawa
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Kinases and Phosphatases
Subjects:
Online Access:https://www.mdpi.com/2813-3757/3/1/3
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