Hsp90 and cochaperones have two genetically distinct roles in regulating eEF2 function.
Protein homeostasis relies on the accurate translation and folding of newly synthesized proteins. Eukaryotic elongation factor 2 (eEF2) promotes GTP-dependent translocation of the ribosome during translation. eEF2 folding was recently shown to be dependent on Hsp90 as well as the cochaperones Hgh1,...
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Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2024-12-01
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Series: | PLoS Genetics |
Online Access: | https://doi.org/10.1371/journal.pgen.1011508 |
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