IGFBP2 and IGFBP4 interact to activate complement pathway in diabetic kidney disease

IGFBP2 and IGFBP4 interact to activate complement pathway in diabetic kidney disease

Background Diabetic kidney disease (DKD) is the leading cause of chronic kidney disease globally. Recent research has identified insulin-like growth factor-binding proteins 2 (IGFBP2) and 4 (IGFBP4) as potential biomarkers for DKD. Overactivation of the complement pathway in DKD remains poorly under...

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Bibliographic Details
Main Authors: Jieling Liang, Yangxiao Huang, Daping Peng, Yali Xie, Yifei Liu, Xiuxia Lu, Junfa Xu
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Renal Failure
Subjects:
Diabetic kidney disease
IGFBP2
IGFBP4
complement pathway
Online Access:https://www.tandfonline.com/doi/10.1080/0886022X.2024.2440528
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https://www.tandfonline.com/doi/10.1080/0886022X.2024.2440528

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