The incoherent feed‐forward loop can generate non‐monotonic input functions for genes

Abstract Gene regulation networks contain recurring circuit patterns called network motifs. One of the most common network motif is the incoherent type 1 feed‐forward loop (I1‐FFL), in which an activator controls both gene and repressor of that gene. This motif was shown to act as a pulse generator...

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Bibliographic Details
Main Authors: Shai Kaplan, Anat Bren, Erez Dekel, Uri Alon
Format: Article
Language:English
Published: Springer Nature 2008-07-01
Series:Molecular Systems Biology
Subjects:
Online Access:https://doi.org/10.1038/msb.2008.43
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