Tumor-To-Tumor Metastasis of Poorly Differentiated Gastric Carcinoma to Uterine Lipoleiomyoma
The rare phenomenon of tumor-to-tumor metastasis was first described in 1930. The donor neoplasm is most frequently lung or breast carcinoma, whereas intracranial meningiomas are reportedly the commonest recipient neoplasm. Here we report a case of metastasis from a primary gastric cancer to a uteri...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Case Reports in Obstetrics and Gynecology |
| Online Access: | http://dx.doi.org/10.1155/2015/352369 |
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| author | Ryo Kiyokoba Hiroshi Yagi Hideaki Yahata Yoshiaki Kawano Eisuke Kaneki Kaoru Okugawa Kenzo Sonoda Kiyoko Kato |
| author_facet | Ryo Kiyokoba Hiroshi Yagi Hideaki Yahata Yoshiaki Kawano Eisuke Kaneki Kaoru Okugawa Kenzo Sonoda Kiyoko Kato |
| author_sort | Ryo Kiyokoba |
| collection | DOAJ |
| description | The rare phenomenon of tumor-to-tumor metastasis was first described in 1930. The donor neoplasm is most frequently lung or breast carcinoma, whereas intracranial meningiomas are reportedly the commonest recipient neoplasm. Here we report a case of metastasis from a primary gastric cancer to a uterine lipoleiomyoma. A 65-year-old woman presented with locally advanced gastric cancer with computed tomography (CT) evidence of peritoneal dissemination and a 9 cm pelvic mass. She underwent 16 courses of TS-1/cisplatin chemotherapy, which achieved significant tumor reduction. However, repeat CT and magnetic resonance imaging revealed a 9 cm diameter pelvic mass adjacent to the uterus. The mass was heterogeneously hyperintense on T1- and T2-weighted images with some low signal spots on fat-suppressed T1-weighted images, suggesting a benign ovarian tumor such as a mature cystic teratoma. After 3 months, pelvic CT revealed a 10 cm multilocular cystic mass that exhibited heterogeneous enhancement after intravenous contrast administration. A diagnostic laparotomy revealed a subserosal uterine tumor extending into the right broad ligament; total abdominal hysterectomy and bilateral salpingo-oophorectomy was performed. The uterine tumor showed histological features of lipoleiomyoma infiltrated by well- to moderately differentiated carcinoma cells that were similar to those of the gastric biopsy, supporting a diagnosis of metastatic gastric adenocarcinoma. |
| format | Article |
| id | doaj-art-92e6ae2994b5494d8e1432b5d8da16ac |
| institution | Kabale University |
| issn | 2090-6684 2090-6692 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Obstetrics and Gynecology |
| spelling | doaj-art-92e6ae2994b5494d8e1432b5d8da16ac2025-02-03T05:46:34ZengWileyCase Reports in Obstetrics and Gynecology2090-66842090-66922015-01-01201510.1155/2015/352369352369Tumor-To-Tumor Metastasis of Poorly Differentiated Gastric Carcinoma to Uterine LipoleiomyomaRyo Kiyokoba0Hiroshi Yagi1Hideaki Yahata2Yoshiaki Kawano3Eisuke Kaneki4Kaoru Okugawa5Kenzo Sonoda6Kiyoko Kato7Department of Obstetrics and Gynecology, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-0052, JapanDepartment of Obstetrics and Gynecology, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-0052, JapanDepartment of Obstetrics and Gynecology, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-0052, JapanDepartment of Obstetrics and Gynecology, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-0052, JapanDepartment of Obstetrics and Gynecology, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-0052, JapanDepartment of Obstetrics and Gynecology, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-0052, JapanDepartment of Obstetrics and Gynecology, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-0052, JapanDepartment of Obstetrics and Gynecology, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-0052, JapanThe rare phenomenon of tumor-to-tumor metastasis was first described in 1930. The donor neoplasm is most frequently lung or breast carcinoma, whereas intracranial meningiomas are reportedly the commonest recipient neoplasm. Here we report a case of metastasis from a primary gastric cancer to a uterine lipoleiomyoma. A 65-year-old woman presented with locally advanced gastric cancer with computed tomography (CT) evidence of peritoneal dissemination and a 9 cm pelvic mass. She underwent 16 courses of TS-1/cisplatin chemotherapy, which achieved significant tumor reduction. However, repeat CT and magnetic resonance imaging revealed a 9 cm diameter pelvic mass adjacent to the uterus. The mass was heterogeneously hyperintense on T1- and T2-weighted images with some low signal spots on fat-suppressed T1-weighted images, suggesting a benign ovarian tumor such as a mature cystic teratoma. After 3 months, pelvic CT revealed a 10 cm multilocular cystic mass that exhibited heterogeneous enhancement after intravenous contrast administration. A diagnostic laparotomy revealed a subserosal uterine tumor extending into the right broad ligament; total abdominal hysterectomy and bilateral salpingo-oophorectomy was performed. The uterine tumor showed histological features of lipoleiomyoma infiltrated by well- to moderately differentiated carcinoma cells that were similar to those of the gastric biopsy, supporting a diagnosis of metastatic gastric adenocarcinoma.http://dx.doi.org/10.1155/2015/352369 |
| spellingShingle | Ryo Kiyokoba Hiroshi Yagi Hideaki Yahata Yoshiaki Kawano Eisuke Kaneki Kaoru Okugawa Kenzo Sonoda Kiyoko Kato Tumor-To-Tumor Metastasis of Poorly Differentiated Gastric Carcinoma to Uterine Lipoleiomyoma Case Reports in Obstetrics and Gynecology |
| title | Tumor-To-Tumor Metastasis of Poorly Differentiated Gastric Carcinoma to Uterine Lipoleiomyoma |
| title_full | Tumor-To-Tumor Metastasis of Poorly Differentiated Gastric Carcinoma to Uterine Lipoleiomyoma |
| title_fullStr | Tumor-To-Tumor Metastasis of Poorly Differentiated Gastric Carcinoma to Uterine Lipoleiomyoma |
| title_full_unstemmed | Tumor-To-Tumor Metastasis of Poorly Differentiated Gastric Carcinoma to Uterine Lipoleiomyoma |
| title_short | Tumor-To-Tumor Metastasis of Poorly Differentiated Gastric Carcinoma to Uterine Lipoleiomyoma |
| title_sort | tumor to tumor metastasis of poorly differentiated gastric carcinoma to uterine lipoleiomyoma |
| url | http://dx.doi.org/10.1155/2015/352369 |
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