Human lncRNAs NEAT1 and MALAT1 regulate the tumor microenvironment in lung cancer PDX models in athymic nude mice

Abstract We employed PDX models in athymic nude mice to generate lung cancer tumors, aiming to improve early detection and enable personalized treatments. The athymic nude mouse was utilized as the lung cancer PDX model, maintaining the histological and pathological integrity of lung cancer. This mo...

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Bibliographic Details
Main Authors: Min-Shiau Hsieh, Meng-Xian Lin, Bing-Ying Ho, Jong-Kai Hsiao
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-05157-z
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