Correcting promoter and beta-lactamase ORF orientation in a widely-used retroviral plasmid to restore bacterial growth

Abstract The pBMN-I-GFP plasmid is a widely used retroviral vector for producing retroviral particles, utilized by thousands of laboratories worldwide. However, we observed that E. coli transformed with pBMN-I-GFP failed to grow on selective LB agar plates containing ampicillin or carbenicillin, in...

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Bibliographic Details
Main Author: Jürgen Wittmann
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-025-93222-y
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