Penile Rehabilitation Therapy with PDE-V Inhibitors Following Radical Prostatectomy: Proceed with Caution
Penile rehabilitation therapy following radical prostatectomy is a much debated topic. Erectile dysfunction is still a significant contributor to postoperative morbidity following radical prostatectomy, despite meticulous nerve-sparing technique. Secondary smooth muscle changes in the penis have be...
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Language: | English |
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Wiley
2009-01-01
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Series: | Advances in Urology |
Online Access: | http://dx.doi.org/10.1155/2009/852437 |
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author | M. Eric Brewer Edward D. Kim |
author_facet | M. Eric Brewer Edward D. Kim |
author_sort | M. Eric Brewer |
collection | DOAJ |
description | Penile rehabilitation therapy following radical prostatectomy is a much debated topic. Erectile dysfunction is still a significant contributor to postoperative morbidity following radical prostatectomy, despite meticulous nerve-sparing technique. Secondary smooth muscle changes in the penis have been identified as the underlying causes of penile atrophy, veno-occlusive dysfunction, and fibrosis. Initial observations that intracavernous injection therapies used on a regular basis postoperatively resulted in improvements in the return of spontaneous erectile function led to the development of penile rehabilitation protocols. Chronic dosing of PDE-V inhibitors is now commonly used by urologists after radical prostatectomy. Despite the current enthusiasm of penile rehabilitation therapy, current scientific evidence with clinical trials is still limited. |
format | Article |
id | doaj-art-928c0ae03a2046a7ac2fcc01d0b2db61 |
institution | Kabale University |
issn | 1687-6369 1687-6377 |
language | English |
publishDate | 2009-01-01 |
publisher | Wiley |
record_format | Article |
series | Advances in Urology |
spelling | doaj-art-928c0ae03a2046a7ac2fcc01d0b2db612025-02-03T07:25:49ZengWileyAdvances in Urology1687-63691687-63772009-01-01200910.1155/2009/852437852437Penile Rehabilitation Therapy with PDE-V Inhibitors Following Radical Prostatectomy: Proceed with CautionM. Eric Brewer0Edward D. Kim1Graduate School of Medicine, The University of Tennessee, Knoxville, TN 37920, USAGraduate School of Medicine, The University of Tennessee, Knoxville, TN 37920, USAPenile rehabilitation therapy following radical prostatectomy is a much debated topic. Erectile dysfunction is still a significant contributor to postoperative morbidity following radical prostatectomy, despite meticulous nerve-sparing technique. Secondary smooth muscle changes in the penis have been identified as the underlying causes of penile atrophy, veno-occlusive dysfunction, and fibrosis. Initial observations that intracavernous injection therapies used on a regular basis postoperatively resulted in improvements in the return of spontaneous erectile function led to the development of penile rehabilitation protocols. Chronic dosing of PDE-V inhibitors is now commonly used by urologists after radical prostatectomy. Despite the current enthusiasm of penile rehabilitation therapy, current scientific evidence with clinical trials is still limited.http://dx.doi.org/10.1155/2009/852437 |
spellingShingle | M. Eric Brewer Edward D. Kim Penile Rehabilitation Therapy with PDE-V Inhibitors Following Radical Prostatectomy: Proceed with Caution Advances in Urology |
title | Penile Rehabilitation Therapy with PDE-V Inhibitors Following Radical Prostatectomy: Proceed with Caution |
title_full | Penile Rehabilitation Therapy with PDE-V Inhibitors Following Radical Prostatectomy: Proceed with Caution |
title_fullStr | Penile Rehabilitation Therapy with PDE-V Inhibitors Following Radical Prostatectomy: Proceed with Caution |
title_full_unstemmed | Penile Rehabilitation Therapy with PDE-V Inhibitors Following Radical Prostatectomy: Proceed with Caution |
title_short | Penile Rehabilitation Therapy with PDE-V Inhibitors Following Radical Prostatectomy: Proceed with Caution |
title_sort | penile rehabilitation therapy with pde v inhibitors following radical prostatectomy proceed with caution |
url | http://dx.doi.org/10.1155/2009/852437 |
work_keys_str_mv | AT mericbrewer penilerehabilitationtherapywithpdevinhibitorsfollowingradicalprostatectomyproceedwithcaution AT edwarddkim penilerehabilitationtherapywithpdevinhibitorsfollowingradicalprostatectomyproceedwithcaution |