Hyper IgE Syndromes: Understanding, Management, and Future Perspectives: A Narrative Review

Hyper IgE Syndromes: Understanding, Management, and Future Perspectives: A Narrative Review

ABSTRACT Background and Aim Hyper IgE syndromes (HIES) are rare primary immunodeficiency characterized by susceptibility to specific infections, eczema, and elevated IgE levels. Pathogenic mutations in STAT3, IL6R, IL6ST, ERBB2IP, PGM3, ZNF431, SPINK5, TGFBR1/2, and CARD11 have been identified as ge...

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Bibliographic Details
Main Authors: Mohammad Salehi, Zeinab Neshati, Hamid Ahanchian, Rana Tafrishi, Alireza Pasdar, Mojtaba Safi, Ehsan Ghayoor Karimiani
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:Health Science Reports
Subjects:
hyper IgE syndromes
inborn errors of immunity
job syndrome
primary immunodeficiency
Online Access:https://doi.org/10.1002/hsr2.70497
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