Submucosal Tunnel Endoscopic Resection for Esophageal Submucosal Tumors: A Multicenter Study
Background. Submucosal tumors (SMTs) are primarily benign tumors, but some may have a malignant potential. Endoscopic submucosal dissection that has been used for removing esophageal SMTs could cause perforation. Submucosal tunnel endoscopic resection (STER) is an improved and an effective technique...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2018/2149564 |
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| author | Sufang Tu Silin Huang Guohua Li Xiaowei Tang Haitao Qing Qiaoping Gao Jingwen Fu Guoping Du Wei Gong |
| author_facet | Sufang Tu Silin Huang Guohua Li Xiaowei Tang Haitao Qing Qiaoping Gao Jingwen Fu Guoping Du Wei Gong |
| author_sort | Sufang Tu |
| collection | DOAJ |
| description | Background. Submucosal tumors (SMTs) are primarily benign tumors, but some may have a malignant potential. Endoscopic submucosal dissection that has been used for removing esophageal SMTs could cause perforation. Submucosal tunnel endoscopic resection (STER) is an improved and an effective technique for treating esophageal SMTs. Aims. This study was conducted to evaluate the efficacy and safety of STER for treating esophageal SMTs. Methods. A retrospective study design was adopted to analyze the baseline characteristics, clinical outcomes, and follow-up data of patients with esophageal SMTs, which originated from the muscularis propria layer and were treated with STER from September 2011 to May 2018. Results. A total of 119 lesions were included from 115 patients who were successfully treated with STER. The mean age of the patients was 49.7 ± 10.7 years. The lesions were primarily located in the middle and lower esophagus. The mean size of the lesions was 19.4 ± 10.0 mm. The mean operation duration was 46.7 ± 25.6 min, and the mean duration of hospitalization was 5.9 ± 2.8 days. The total en bloc resection rate and the complete resection rate were 97.5% and 100%, respectively. Regarding complications, there were 9 (7.8%) cases of perforation, 2 (1.7%) cases of pneumothorax, and 9 (7.8%) cases of subcutaneous emphysema. Histopathological results revealed 113 (95.0%) cases of leiomyoma, 5 (4.2%) cases of gastrointestinal stromal tumors, and 1 (0.8%) case of a granular cell tumor. During the mean 15-month follow-up, there were no cases of recurrence and distant metastasis. Conclusions. STER is a safe and feasible technique for treating esophageal SMTs originating from the muscularis propria layer. |
| format | Article |
| id | doaj-art-921bbea94a704fadb3cbfe56a49180fd |
| institution | Kabale University |
| issn | 1687-6121 1687-630X |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Gastroenterology Research and Practice |
| spelling | doaj-art-921bbea94a704fadb3cbfe56a49180fd2025-02-03T01:00:01ZengWileyGastroenterology Research and Practice1687-61211687-630X2018-01-01201810.1155/2018/21495642149564Submucosal Tunnel Endoscopic Resection for Esophageal Submucosal Tumors: A Multicenter StudySufang Tu0Silin Huang1Guohua Li2Xiaowei Tang3Haitao Qing4Qiaoping Gao5Jingwen Fu6Guoping Du7Wei Gong8Department of Gastroenterology, Nanfang Hospital, Southern Medical University, Guangzhou, ChinaDepartment of Gastroenterology, Nanfang Hospital, Southern Medical University, Guangzhou, ChinaDepartment of Gastroenterology, Shunde Hospital, Southern Medical University, Foshan, ChinaDepartment of Gastroenterology, Affiliated Hospital of Southwest Medical University, Luzhou, ChinaDepartment of Gastroenterology, Nanfang Hospital, Southern Medical University, Guangzhou, ChinaDepartment of Gastroenterology, Nanfang Hospital, Southern Medical University, Guangzhou, ChinaDepartment of Gastroenterology, Nanfang Hospital, Southern Medical University, Guangzhou, ChinaDepartment of Gastroenterology, Shunde Hospital, Southern Medical University, Foshan, ChinaDepartment of Gastroenterology, Nanfang Hospital, Southern Medical University, Guangzhou, ChinaBackground. Submucosal tumors (SMTs) are primarily benign tumors, but some may have a malignant potential. Endoscopic submucosal dissection that has been used for removing esophageal SMTs could cause perforation. Submucosal tunnel endoscopic resection (STER) is an improved and an effective technique for treating esophageal SMTs. Aims. This study was conducted to evaluate the efficacy and safety of STER for treating esophageal SMTs. Methods. A retrospective study design was adopted to analyze the baseline characteristics, clinical outcomes, and follow-up data of patients with esophageal SMTs, which originated from the muscularis propria layer and were treated with STER from September 2011 to May 2018. Results. A total of 119 lesions were included from 115 patients who were successfully treated with STER. The mean age of the patients was 49.7 ± 10.7 years. The lesions were primarily located in the middle and lower esophagus. The mean size of the lesions was 19.4 ± 10.0 mm. The mean operation duration was 46.7 ± 25.6 min, and the mean duration of hospitalization was 5.9 ± 2.8 days. The total en bloc resection rate and the complete resection rate were 97.5% and 100%, respectively. Regarding complications, there were 9 (7.8%) cases of perforation, 2 (1.7%) cases of pneumothorax, and 9 (7.8%) cases of subcutaneous emphysema. Histopathological results revealed 113 (95.0%) cases of leiomyoma, 5 (4.2%) cases of gastrointestinal stromal tumors, and 1 (0.8%) case of a granular cell tumor. During the mean 15-month follow-up, there were no cases of recurrence and distant metastasis. Conclusions. STER is a safe and feasible technique for treating esophageal SMTs originating from the muscularis propria layer.http://dx.doi.org/10.1155/2018/2149564 |
| spellingShingle | Sufang Tu Silin Huang Guohua Li Xiaowei Tang Haitao Qing Qiaoping Gao Jingwen Fu Guoping Du Wei Gong Submucosal Tunnel Endoscopic Resection for Esophageal Submucosal Tumors: A Multicenter Study Gastroenterology Research and Practice |
| title | Submucosal Tunnel Endoscopic Resection for Esophageal Submucosal Tumors: A Multicenter Study |
| title_full | Submucosal Tunnel Endoscopic Resection for Esophageal Submucosal Tumors: A Multicenter Study |
| title_fullStr | Submucosal Tunnel Endoscopic Resection for Esophageal Submucosal Tumors: A Multicenter Study |
| title_full_unstemmed | Submucosal Tunnel Endoscopic Resection for Esophageal Submucosal Tumors: A Multicenter Study |
| title_short | Submucosal Tunnel Endoscopic Resection for Esophageal Submucosal Tumors: A Multicenter Study |
| title_sort | submucosal tunnel endoscopic resection for esophageal submucosal tumors a multicenter study |
| url | http://dx.doi.org/10.1155/2018/2149564 |
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