Real-world validation study of the LSC17 score for risk prediction in patients with newly diagnosed acute myeloid leukemia

Acute myeloid leukemia (AML) patients exhibit diverse molecular and cytogenetic changes with heterogeneous outcomes. The functionally-derived LSC17 gene expression score has demonstrated strong prognostic significance in retrospective analyses of adult and pediatric AML cohorts, where above-median...

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Main Authors: Tracy Murphy, Boyang Zhang, Tong Zhang, Ian King, Jose-Mario Capo-Chichi, Vikas Gupta, Dawn Maze, Caroline J. McNamara, Mark D. Minden, Aaron D. Schimmer, Andre C. Schuh, Hassan Sibai, Karen W.L. Yee, Andrea Arruda, Zhibin Lu, Dina Khalaf, Chantal Rockwell, Brian Leber, Mitchell Sabloff, Anne Tierens, Tracy L. Stockley, Steven M. Chan, Stanley W.K. Ng, Jean C.Y. Wang
Format: Article
Language:English
Published: Ferrata Storti Foundation 2025-07-01
Series:Haematologica
Online Access:https://haematologica.org/article/view/12171
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