Adrenal crisis due to pembrolizumab-induced hypophysitis in a patient with triple-negative breast cancer

Adrenal crisis due to pembrolizumab-induced hypophysitis in a patient with triple-negative breast cancer

We report a case of a 43-year-old woman with stage IIB triple-negative breast cancer (TNBC) on neoadjuvant pembrolizumab presenting in adrenal crisis. Biochemical evaluation revealed isolated adrenocorticotropic hormone (ACTH) deficiency, and MRI demonstrated a partial empty sella; findings consiste...

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Bibliographic Details
Main Authors: Sobrina S Mohammed, Sallam Alrosan, Reda Asad
Format: Article
Language:English
Published: Bioscientifica 2025-06-01
Series:Endocrine Oncology
Subjects:
adrenal
crisis
pembrolizumab
induced
hypophysitis
Online Access:https://eo.bioscientifica.com/view/journals/eo/5/1/EO-25-0046.xml
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