Label-free isolation of lipid-rich Saccharomyces cerevisiae mutant by high-throughput flow-mode Raman-activated cell sorting and multi-omics analysis for uncovering the mechanism of enhanced lipid accumulation

Abstract Background Palmitoleic acid, a valuable functional fatty acid, is notably scarce in traditional oil crops, with the exception of certain wild plants such as macadamia nuts and sea buckthorn. Recently, the lipid from Saccharomyces cerevisiae was found to contain approximately 50% palmitoleic...

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Bibliographic Details
Main Authors: Xiaotong Ji, Xixian Wang, Wenjun Zhou, Lin Chen, Tianzhong Liu, Jian Xu, Bo Ma
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Biotechnology for Biofuels and Bioproducts
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Online Access:https://doi.org/10.1186/s13068-025-02677-8
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