Antimicrobial peptide Hs02 with rapid bactericidal, anti-biofilm, and anti-inflammatory activity against carbapenem-resistant Klebsiella pneumoniae and Escherichia coli

Antimicrobial peptide Hs02 with rapid bactericidal, anti-biofilm, and anti-inflammatory activity against carbapenem-resistant Klebsiella pneumoniae and Escherichia coli

ABSTRACT Carbapenem-resistant Klebsiella pneumoniae (CRKP) and Escherichia coli (CREC) are frequently detected in clinical settings, restricting the use of carbapenems. Therefore, there is an urgent need for new antimicrobial strategies to address infections caused by CRKP and CREC. This study inves...

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Bibliographic Details
Main Authors: Deyi Zhao, Miran Tang, Panjie Hu, Xiaowei Hu, Weijun Chen, Zhexiao Ma, Huanchang Chen, Haifeng Liu, Jianming Cao, Tieli Zhou
Format: Article
Language:English
Published: American Society for Microbiology 2025-01-01
Series:Microbiology Spectrum
Subjects:
antimicrobial peptides
Hs02
carbapenem-resistance
LPS neutralization
Online Access:https://journals.asm.org/doi/10.1128/spectrum.01050-24
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https://journals.asm.org/doi/10.1128/spectrum.01050-24

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