Oncological principles in the management of ocular surface squamous neoplasia - A Review
Ocular surface squamous neoplasia (OSSN) is the most common neoplasia of the anterior segment. Accurate and timely diagnosis, including detailed clinical assessment and imaging, is essential to ascertain the extent of the disease. The gold standard treatment for OSSN has evolved over the years, tran...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2025-02-01
|
| Series: | Indian Journal of Ophthalmology |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/IJO.IJO_2340_24 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832087237419859968 |
|---|---|
| author | Rolika Bansal Santosh G Honavar |
| author_facet | Rolika Bansal Santosh G Honavar |
| author_sort | Rolika Bansal |
| collection | DOAJ |
| description | Ocular surface squamous neoplasia (OSSN) is the most common neoplasia of the anterior segment. Accurate and timely diagnosis, including detailed clinical assessment and imaging, is essential to ascertain the extent of the disease. The gold standard treatment for OSSN has evolved over the years, transitioning from wide-margin surgical excision using the “no-touch” technique to topical immunotherapy, plaque brachytherapy, and targeted immunotherapy. The choice of treatment modality depends on a tailored approach based on the initial presentation and progression of the disease. This review consolidates a comprehensive understanding of the variable clinical presentations of OSSN, diagnostic and imaging techniques, and available treatment options. It also provides a foundation for the oncologic principles of managing OSSN while offering insights into future therapeutic approaches. |
| format | Article |
| id | doaj-art-90ed66d2f1a84be19257fb07a5860879 |
| institution | Kabale University |
| issn | 0301-4738 1998-3689 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Ophthalmology |
| spelling | doaj-art-90ed66d2f1a84be19257fb07a58608792025-02-06T05:39:35ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892025-02-0173217319010.4103/IJO.IJO_2340_24Oncological principles in the management of ocular surface squamous neoplasia - A ReviewRolika BansalSantosh G HonavarOcular surface squamous neoplasia (OSSN) is the most common neoplasia of the anterior segment. Accurate and timely diagnosis, including detailed clinical assessment and imaging, is essential to ascertain the extent of the disease. The gold standard treatment for OSSN has evolved over the years, transitioning from wide-margin surgical excision using the “no-touch” technique to topical immunotherapy, plaque brachytherapy, and targeted immunotherapy. The choice of treatment modality depends on a tailored approach based on the initial presentation and progression of the disease. This review consolidates a comprehensive understanding of the variable clinical presentations of OSSN, diagnostic and imaging techniques, and available treatment options. It also provides a foundation for the oncologic principles of managing OSSN while offering insights into future therapeutic approaches.https://journals.lww.com/10.4103/IJO.IJO_2340_245-fluorouracilconjunctival neoplasiacorneal neoplasiainterferon α-2bmitomycin-cocular surface squamous neoplasiaplaque brachytherapyplaque radiotherapysquamous cell carcinomasystemic immunotherapytargeted therapytopical chemotherapy |
| spellingShingle | Rolika Bansal Santosh G Honavar Oncological principles in the management of ocular surface squamous neoplasia - A Review Indian Journal of Ophthalmology 5-fluorouracil conjunctival neoplasia corneal neoplasia interferon α-2b mitomycin-c ocular surface squamous neoplasia plaque brachytherapy plaque radiotherapy squamous cell carcinoma systemic immunotherapy targeted therapy topical chemotherapy |
| title | Oncological principles in the management of ocular surface squamous neoplasia - A Review |
| title_full | Oncological principles in the management of ocular surface squamous neoplasia - A Review |
| title_fullStr | Oncological principles in the management of ocular surface squamous neoplasia - A Review |
| title_full_unstemmed | Oncological principles in the management of ocular surface squamous neoplasia - A Review |
| title_short | Oncological principles in the management of ocular surface squamous neoplasia - A Review |
| title_sort | oncological principles in the management of ocular surface squamous neoplasia a review |
| topic | 5-fluorouracil conjunctival neoplasia corneal neoplasia interferon α-2b mitomycin-c ocular surface squamous neoplasia plaque brachytherapy plaque radiotherapy squamous cell carcinoma systemic immunotherapy targeted therapy topical chemotherapy |
| url | https://journals.lww.com/10.4103/IJO.IJO_2340_24 |
| work_keys_str_mv | AT rolikabansal oncologicalprinciplesinthemanagementofocularsurfacesquamousneoplasiaareview AT santoshghonavar oncologicalprinciplesinthemanagementofocularsurfacesquamousneoplasiaareview |