PRMT1 Promotes the Self‐renewal of Leukemia Stem Cells by Regulating Protein Synthesis

PRMT1 Promotes the Self‐renewal of Leukemia Stem Cells by Regulating Protein Synthesis

Abstract The application of tyrosine kinase inhibitors (TKIs) has revolutionized the management of chronic myeloid leukemia (CML). However, disease relapse and progression particularly due to persistent leukemia stem cells (LSCs) remain a big challenge in the clinic. Therefore, validation of the the...

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Bibliographic Details
Main Authors: Min Zhou, Yi Huang, Ping Xu, Shuyi Li, Chen Duan, Xiaoying Lin, Shilai Bao, Waiyi Zou, Jingxuan Pan, Chang Liu, Yanli Jin
Format: Article
Language:English
Published: Wiley 2025-02-01
Series:Advanced Science
Subjects:
CML
leukemia stem cells
PRMT1
protein synthesis
RPL29
self‐renewal
Online Access:https://doi.org/10.1002/advs.202308586
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