Integrating bioinformatics and machine learning to identify biomarkers of branched chain amino acid related genes in osteoarthritis

Integrating bioinformatics and machine learning to identify biomarkers of branched chain amino acid related genes in osteoarthritis

Abstract Background Branched-chain amino acids (BCAA) metabolism is significantly associated with osteoarthritis (OA), but the specific mechanism of BCAA related genes (BCAA-RGs) in OA is still unclear. Therefore, this research intended to identify potential biomarkers and mechanisms of action of BC...

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Bibliographic Details
Main Authors: Xiao-Zhi ZhaYang, Yan-Xiong Chen, Wen-Da Hua, Zheng-Lin Bai, Yun-Peng Jin, Xing-Wen Zhao, Quan-Fu Liu, Zeng-Dong Meng
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Musculoskeletal Disorders
Subjects:
Osteoarthritis
Branched-chain amino acids
Machine learning
Bioinformatic analysis
Drug prediction
Online Access:https://doi.org/10.1186/s12891-025-08779-6
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