ChromaFold predicts the 3D contact map from single-cell chromatin accessibility
Abstract Identifying cell-type-specific 3D chromatin interactions between regulatory elements can help decipher gene regulation and interpret disease-associated non-coding variants. However, achieving this resolution with current 3D genomics technologies is often infeasible given limited input cell...
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Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2024-11-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-024-53628-0 |
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