Melanin-concentrating hormone attenuates the hedonic feeding induced by orexin-A in the ventral tegmental area of high-fat diet male mice

Melanin-concentrating hormone attenuates the hedonic feeding induced by orexin-A in the ventral tegmental area of high-fat diet male mice

ObjectiveThe ventral tegmental area (VTA), a pivotal hub in the brain’s reward circuitry, receives inputs from the lateral hypothalamic area (LHA). However, it remains unclear whether melanin-concentrating hormone (MCH) and orexin-A (OX-A) neurons in the LHA exert individual or cooperative influence...

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Bibliographic Details
Main Authors: Xiaoning Liu, Helin Yang, Wenguang Xu, Xuezhe Wang, Wenhui Tang, Xiaoxuan Wang, Yang Jiao, Xinchi Luan, Pengmeng Li, Feifei Guo
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Nutrition
Subjects:
lateral hypothalamic area
ventral tegmental area
melanin-concentrating hormone
orexin-A
hedonic feeding
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2024.1468874/full
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