Mediators of Inflammation and Their Effect on Resident Renal Cells: Implications in Lupus Nephritis
Lupus nephritis affects up to 70% of patients with systemic lupus erythematosus and is a major cause of morbidity and mortality. It is characterized by a breakdown of immune tolerance, production of autoantibodies, and deposition of immune complexes within the kidney parenchyma, resulting in local i...
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Main Authors: | Susan Yung, Kwok Fan Cheung, Qing Zhang, Tak Mao Chan |
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Format: | Article |
Language: | English |
Published: |
Wiley
2013-01-01
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Series: | Clinical and Developmental Immunology |
Online Access: | http://dx.doi.org/10.1155/2013/317682 |
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