Mediators of Inflammation and Their Effect on Resident Renal Cells: Implications in Lupus Nephritis

Lupus nephritis affects up to 70% of patients with systemic lupus erythematosus and is a major cause of morbidity and mortality. It is characterized by a breakdown of immune tolerance, production of autoantibodies, and deposition of immune complexes within the kidney parenchyma, resulting in local i...

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Bibliographic Details
Main Authors: Susan Yung, Kwok Fan Cheung, Qing Zhang, Tak Mao Chan
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Clinical and Developmental Immunology
Online Access:http://dx.doi.org/10.1155/2013/317682
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