Metabolic reprogramming of glucose: the metabolic basis for the occurrence and development of hepatocellular carcinoma

Metabolic reprogramming of glucose: the metabolic basis for the occurrence and development of hepatocellular carcinoma

Primary liver cancer is a common malignant tumor of the digestive system, with hepatocellular carcinoma (HCC) being the most prevalent type. It is characterized by high malignancy, insidious onset, and a lack of specific early diagnostic and therapeutic markers, posing a serious threat to human heal...

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Bibliographic Details
Main Authors: Kai Wang, Xiaodan Li, Shuwei Guo, Junsheng Chen, Yandong Lv, Zhiqiang Guo, Hongzhou Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Oncology
Subjects:
hepatocellular carcinoma (HCC)
metabolic reprogramming
glucose metabolism
glycolytic pathway
pentose phosphate pathway (PPP)
gluconeogenesis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1545086/full
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