Exploratory analyses of factors related to 5-aminolevulinic acid-induced intraoperative hypotension during malignant glioma surgery via literature review

Background: Photodynamic diagnosis using 5-aminolevulinic acid (5ALA) improves glioma resection but has been associated with intraoperative hypotension (IOH), particularly in Japan. Although nitric oxide (NO) production has been suggested as a mechanism, the pathophysiology remains unclear. Methods:...

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Bibliographic Details
Main Authors: Kyoichi Tomoto, Akihiko Teshigawara, Tomohiro Aoki, Masahiko Itani, Yuzuru Hasegawa, Yuichi Murayama, Toshihide Tanaka
Format: Article
Language:English
Published: Elsevier 2025-10-01
Series:Photodiagnosis and Photodynamic Therapy
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Online Access:http://www.sciencedirect.com/science/article/pii/S1572100025002078
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