Hybrid Sindbis/Epstein-Barr virus episomal expression vector for inducible production of proteins

Alphavirus vectors are attractive as recombinant protein expression systems due to the high level of gene expression achieved. The combination of two mutations in the viral replicase, which render the replicase noncytopathic and temperature-sensitive, allowed the generation of a DNA-based vector (Cy...

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Bibliographic Details
Main Authors: Lidia Ivanova, Johanna Brändli, Philippe Saudan, Martin F. Bachmann
Format: Article
Language:English
Published: Taylor & Francis Group 2005-08-01
Series:BioTechniques
Online Access:https://www.future-science.com/doi/10.2144/05392ST03
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