Efficacy and Safety of Adalimumab in Canadian Patients with Moderate to Severe Crohn’s Disease: Results of the Adalimumab in Canadian SubjeCts with ModErate to Severe Crohn’s DiseaSe (ACCESS) Trial

OBJECTIVE: To evaluate open-label adalimumab therapy for clinical effectiveness, fistula healing, patient-reported outcomes and safety in Canadian patients with moderate to severe Crohn’s disease (CD) who were either naive to or previously exposed to antitumour necrosis factor (anti-TNF) therapy.

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Main Authors: Remo Panaccione, Edward V Loftus, David Binion, Kevin McHugh, Shamsul Alam, Naijun Chen, Benoît Guérette, Parvez Mulani, Jingdong Chao
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Canadian Journal of Gastroenterology
Online Access:http://dx.doi.org/10.1155/2011/724813
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author Remo Panaccione
Edward V Loftus
David Binion
Kevin McHugh
Shamsul Alam
Naijun Chen
Benoît Guérette
Parvez Mulani
Jingdong Chao
author_facet Remo Panaccione
Edward V Loftus
David Binion
Kevin McHugh
Shamsul Alam
Naijun Chen
Benoît Guérette
Parvez Mulani
Jingdong Chao
author_sort Remo Panaccione
collection DOAJ
description OBJECTIVE: To evaluate open-label adalimumab therapy for clinical effectiveness, fistula healing, patient-reported outcomes and safety in Canadian patients with moderate to severe Crohn’s disease (CD) who were either naive to or previously exposed to antitumour necrosis factor (anti-TNF) therapy.
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publishDate 2011-01-01
publisher Wiley
record_format Article
series Canadian Journal of Gastroenterology
spelling doaj-art-8fc99cce04214177a1efc118cfa7fc8f2025-02-03T00:59:29ZengWileyCanadian Journal of Gastroenterology0835-79002011-01-0125841942510.1155/2011/724813Efficacy and Safety of Adalimumab in Canadian Patients with Moderate to Severe Crohn’s Disease: Results of the Adalimumab in Canadian SubjeCts with ModErate to Severe Crohn’s DiseaSe (ACCESS) TrialRemo Panaccione0Edward V Loftus1David Binion2Kevin McHugh3Shamsul Alam4Naijun Chen5Benoît Guérette6Parvez Mulani7Jingdong Chao8University of Calgary, Calgary, Alberta, CanadaDivision of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USAUniversity of Pittsburgh, Pittsburgh, Pennsylvania, USAAbbott Laboratories, Montreal, Quebec, CanadaAbbott Laboratories, Abbott Park, Illinois, USAAbbott Laboratories, Abbott Park, Illinois, USAAbbott Laboratories, Rungis, FranceAbbott Laboratories, Abbott Park, Illinois, USAAbbott Laboratories, Abbott Park, Illinois, USAOBJECTIVE: To evaluate open-label adalimumab therapy for clinical effectiveness, fistula healing, patient-reported outcomes and safety in Canadian patients with moderate to severe Crohn’s disease (CD) who were either naive to or previously exposed to antitumour necrosis factor (anti-TNF) therapy.http://dx.doi.org/10.1155/2011/724813
spellingShingle Remo Panaccione
Edward V Loftus
David Binion
Kevin McHugh
Shamsul Alam
Naijun Chen
Benoît Guérette
Parvez Mulani
Jingdong Chao
Efficacy and Safety of Adalimumab in Canadian Patients with Moderate to Severe Crohn’s Disease: Results of the Adalimumab in Canadian SubjeCts with ModErate to Severe Crohn’s DiseaSe (ACCESS) Trial
Canadian Journal of Gastroenterology
title Efficacy and Safety of Adalimumab in Canadian Patients with Moderate to Severe Crohn’s Disease: Results of the Adalimumab in Canadian SubjeCts with ModErate to Severe Crohn’s DiseaSe (ACCESS) Trial
title_full Efficacy and Safety of Adalimumab in Canadian Patients with Moderate to Severe Crohn’s Disease: Results of the Adalimumab in Canadian SubjeCts with ModErate to Severe Crohn’s DiseaSe (ACCESS) Trial
title_fullStr Efficacy and Safety of Adalimumab in Canadian Patients with Moderate to Severe Crohn’s Disease: Results of the Adalimumab in Canadian SubjeCts with ModErate to Severe Crohn’s DiseaSe (ACCESS) Trial
title_full_unstemmed Efficacy and Safety of Adalimumab in Canadian Patients with Moderate to Severe Crohn’s Disease: Results of the Adalimumab in Canadian SubjeCts with ModErate to Severe Crohn’s DiseaSe (ACCESS) Trial
title_short Efficacy and Safety of Adalimumab in Canadian Patients with Moderate to Severe Crohn’s Disease: Results of the Adalimumab in Canadian SubjeCts with ModErate to Severe Crohn’s DiseaSe (ACCESS) Trial
title_sort efficacy and safety of adalimumab in canadian patients with moderate to severe crohn s disease results of the adalimumab in canadian subjects with moderate to severe crohn s disease access trial
url http://dx.doi.org/10.1155/2011/724813
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