Scutellaria barbata D.Don and Hedyotis diffusa Willd herb pair combined with cisplatin synergistically inhibits ovarian cancer progression through modulating oxidative stress via NRF2-FTH1 autophagic degradation pathway

Scutellaria barbata D.Don and Hedyotis diffusa Willd herb pair combined with cisplatin synergistically inhibits ovarian cancer progression through modulating oxidative stress via NRF2-FTH1 autophagic degradation pathway

Abstract Background Cisplatin (DDP) is one of the most effective anticancer drugs, commonly used to treat advanced ovarian cancer (OC). However, DDP has significant limitations of platinum-based drugs, including chemical resistance and high-dose toxic side effects. Traditional Chinese medicines (TCM...

Full description

Saved in:
Bibliographic Details
Main Authors: Xue Sui, Bingqing Gao, Liu Zhang, Yanmin Wang, Junnan Ma, Xingchen Wu, Chenyu Zhou, Min Liu, Lin Zhang
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Journal of Ovarian Research
Subjects:
Scutellaria barbata D.Don and Hedyotis diffusa Willd
Ovarian cancer
DDP chemosensitivity
NRF2/HO-1
Oxidative stress
Ferritin autophagic degradation
Online Access:https://doi.org/10.1186/s13048-024-01570-6
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1186/s13048-024-01570-6

Similar Items