Arachidonic acid suppresses lung cancer cell growth and modulates lipid metabolism and the ERK/PPARγ signaling pathway

Arachidonic acid suppresses lung cancer cell growth and modulates lipid metabolism and the ERK/PPARγ signaling pathway

Abstract Lung cancer remains the leading cause of cancer-related mortality worldwide, necessitating the development of new treatment strategies. Arachidonic acid (ARA), a polyunsaturated fatty acid, shows promise in cancer therapy due to its potential anti-tumor effects, although its role in lung ca...

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Bibliographic Details
Main Authors: Lin Wang, Lanlan Wei, Xueling Chen, Jiali Xiong
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Lipids in Health and Disease
Subjects:
Arachidonic acid (ARA)
Lung cancer
The extracellular signal-regulated kinase (ERK)/peroxisome proliferator-activated receptor gamma (PPARγ) pathway
Lipid metabolism
Mitogen-activated protein kinase 1 (MAPK1)
Online Access:https://doi.org/10.1186/s12944-025-02490-0
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https://doi.org/10.1186/s12944-025-02490-0

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