Expanding the scope of mast cell disease: Does mast cell‐derived TNF play a role in immune‐mediated chronic illness and autoimmunity?

Expanding the scope of mast cell disease: Does mast cell‐derived TNF play a role in immune‐mediated chronic illness and autoimmunity?

Abstract Increasing evidence underscores the vital significance of diverse mast cell mediators in inflammatory illness, yet diagnostic criteria for mast cell activation syndrome still focus predominantly on a solitary mediator, tryptase. Therapeutic interventions, conversely, tend to prioritize hist...

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Bibliographic Details
Main Authors: Rachel da Silveira Gorman, Iffath Unissa Syed
Format: Article
Language:English
Published: Wiley 2024-12-01
Series:Rheumatology & Autoimmunity
Subjects:
autoimmune disease
chronic illness
mast cells
mast cell activation syndrome
mitochondrial dysfunction
tumor necrosis factor
Online Access:https://doi.org/10.1002/rai2.12151
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https://doi.org/10.1002/rai2.12151

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