Repurposing antiviral drugs targeting the PARP-1 and HER2 pathways with multifaceted impacts through integrated network analysis and molecular mechanics

This study investigates the anticancer potential of existing anti-viral drugs using a comprehensive suite of computational methods. A dataset of 76 antiviral drugs was prepared and optimized for analysis. Through the application of network pharmacology, gene ontology, and Kyoto Encyclopedia of Genes...

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Bibliographic Details
Main Authors: Uma Maheshwari Mugundan, Praveen Sekar, Rajanandh Muhasaparur Ganesan
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Chemical Physics Impact
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Online Access:http://www.sciencedirect.com/science/article/pii/S2667022424003566
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