Temperature-Responsive Gelation of Type I Collagen Solutions Involving Fibril Formation and Genipin Crosslinking as a Potential Injectable Hydrogel
We investigated the temperature-responsive gelation of collagen/genipin solutions using pepsin-solubilized collagen (PSC) and acid-solubilized collagen (ASC) as substrates. Gelation occurred in the PSC/genipin solutions at genipin concentrations 0–2 mM under moderate change in temperature from 25 to...
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Main Authors: | Shunji Yunoki, Yoshimi Ohyabu, Hirosuke Hatayama |
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Format: | Article |
Language: | English |
Published: |
Wiley
2013-01-01
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Series: | International Journal of Biomaterials |
Online Access: | http://dx.doi.org/10.1155/2013/620765 |
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