Incidence Of Hypoparathyroidism After Total Thyroidectomy for Benign Goitres. A Systematic Review
Objective: systematic review assessed the overall incidence of hypoparathyroidism after Total thyroidectomy (TT) for benign goitres. Methods: A systematic search of PubMed, google scholar, Cochrane, and Pakmedinet under PRISMA (preferred reporting items for systematic reviews and Meta-analyses)...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Rawalpindi Medical University
2023-06-01
|
| Series: | Journal of Rawalpindi Medical College |
| Online Access: | https://www.journalrmc.com/index.php/JRMC/article/view/2058 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832086955327750144 |
|---|---|
| author | Muhammad Tahir Ghani Hafiz Muhammad Ijaz ul Haq Ibad Ur Rehman Huma Azam Malik |
| author_facet | Muhammad Tahir Ghani Hafiz Muhammad Ijaz ul Haq Ibad Ur Rehman Huma Azam Malik |
| author_sort | Muhammad Tahir Ghani |
| collection | DOAJ |
| description |
Objective: systematic review assessed the overall incidence of hypoparathyroidism after Total thyroidectomy (TT) for benign goitres.
Methods: A systematic search of PubMed, google scholar, Cochrane, and Pakmedinet under PRISMA (preferred reporting items for systematic reviews and Meta-analyses) guidelines was performed. All studies during the last 50 years where TT was performed for benign goitres and post-operative hypoparathyroidism was assessed were included. The total incidence of both transient and permanent hypoparathyroidism was calculated after TT for benign goitres. The risk of bias was also assessed.
Results: Twelve studies were included in total including eight retrospective, three prospective observational studies, and one randomized trial. Three studies were from Turkey, 2 from Pakistan, 2 from Greece, and one each from Saudi Arabia, India, Denmark, Egypt, and the USA. 2809 TT were performed for benign goitres. Overall Transient hypoparathyroidism (THP) was noted in 290 (10%) patients while permanent hypoparathyroidism (PHP) was noted in 33(1.17%) patients. The highest incidence of permanent hypoparathyroidism was 17% in one study while the lowest was 0% in three studies. The highest incidence of transient hypoparathyroidism was 28.5% in one study while the lowest incidence was 2.5%. The risk of bias was high.
Conclusion: TT for benign goitres is associated with 1.17 % overall risk (range 0%-17%) of PHP and 10% (range 2.5%-28.5%) of THP.
|
| format | Article |
| id | doaj-art-8ea2aa64585e41fe8368765f19747f9f |
| institution | Kabale University |
| issn | 1683-3562 1683-3570 |
| language | English |
| publishDate | 2023-06-01 |
| publisher | Rawalpindi Medical University |
| record_format | Article |
| series | Journal of Rawalpindi Medical College |
| spelling | doaj-art-8ea2aa64585e41fe8368765f19747f9f2025-02-06T08:41:52ZengRawalpindi Medical UniversityJournal of Rawalpindi Medical College1683-35621683-35702023-06-0127210.37939/jrmc.v27i2.2058Incidence Of Hypoparathyroidism After Total Thyroidectomy for Benign Goitres. A Systematic Review Muhammad Tahir GhaniHafiz Muhammad Ijaz ul HaqIbad Ur RehmanHuma Azam Malik Objective: systematic review assessed the overall incidence of hypoparathyroidism after Total thyroidectomy (TT) for benign goitres. Methods: A systematic search of PubMed, google scholar, Cochrane, and Pakmedinet under PRISMA (preferred reporting items for systematic reviews and Meta-analyses) guidelines was performed. All studies during the last 50 years where TT was performed for benign goitres and post-operative hypoparathyroidism was assessed were included. The total incidence of both transient and permanent hypoparathyroidism was calculated after TT for benign goitres. The risk of bias was also assessed. Results: Twelve studies were included in total including eight retrospective, three prospective observational studies, and one randomized trial. Three studies were from Turkey, 2 from Pakistan, 2 from Greece, and one each from Saudi Arabia, India, Denmark, Egypt, and the USA. 2809 TT were performed for benign goitres. Overall Transient hypoparathyroidism (THP) was noted in 290 (10%) patients while permanent hypoparathyroidism (PHP) was noted in 33(1.17%) patients. The highest incidence of permanent hypoparathyroidism was 17% in one study while the lowest was 0% in three studies. The highest incidence of transient hypoparathyroidism was 28.5% in one study while the lowest incidence was 2.5%. The risk of bias was high. Conclusion: TT for benign goitres is associated with 1.17 % overall risk (range 0%-17%) of PHP and 10% (range 2.5%-28.5%) of THP. https://www.journalrmc.com/index.php/JRMC/article/view/2058 |
| spellingShingle | Muhammad Tahir Ghani Hafiz Muhammad Ijaz ul Haq Ibad Ur Rehman Huma Azam Malik Incidence Of Hypoparathyroidism After Total Thyroidectomy for Benign Goitres. A Systematic Review Journal of Rawalpindi Medical College |
| title | Incidence Of Hypoparathyroidism After Total Thyroidectomy for Benign Goitres. A Systematic Review |
| title_full | Incidence Of Hypoparathyroidism After Total Thyroidectomy for Benign Goitres. A Systematic Review |
| title_fullStr | Incidence Of Hypoparathyroidism After Total Thyroidectomy for Benign Goitres. A Systematic Review |
| title_full_unstemmed | Incidence Of Hypoparathyroidism After Total Thyroidectomy for Benign Goitres. A Systematic Review |
| title_short | Incidence Of Hypoparathyroidism After Total Thyroidectomy for Benign Goitres. A Systematic Review |
| title_sort | incidence of hypoparathyroidism after total thyroidectomy for benign goitres a systematic review |
| url | https://www.journalrmc.com/index.php/JRMC/article/view/2058 |
| work_keys_str_mv | AT muhammadtahirghani incidenceofhypoparathyroidismaftertotalthyroidectomyforbenigngoitresasystematicreview AT hafizmuhammadijazulhaq incidenceofhypoparathyroidismaftertotalthyroidectomyforbenigngoitresasystematicreview AT ibadurrehman incidenceofhypoparathyroidismaftertotalthyroidectomyforbenigngoitresasystematicreview AT humaazammalik incidenceofhypoparathyroidismaftertotalthyroidectomyforbenigngoitresasystematicreview |