BCAA insufficiency leads to premature ovarian insufficiency via ceramide‐induced elevation of ROS

BCAA insufficiency leads to premature ovarian insufficiency via ceramide‐induced elevation of ROS

Abstract Premature ovarian insufficiency (POI) is a disease featured by early menopause before 40 years of age, accompanied by an elevation of follicle‐stimulating hormone. Though POI affects many aspects of women's health, its major causes remain unknown. Many clinical studies have shown that...

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Main Authors: Xiao Guo, Yuemeng Zhu, Lu Guo, Yiwen Qi, Xiaocheng Liu, Jinhui Wang, Jiangtao Zhang, Linlin Cui, Yueyang Shi, Qichu Wang, Cenxi Liu, Guangxing Lu, Yilian Liu, Tao Li, Shangyu Hong, Yingying Qin, Xuelian Xiong, Hao Wu, Lin Huang, He Huang, Chao Gu, Bin Li, Jin Li
Format: Article
Language:English
Published: Springer Nature 2023-02-01
Series:EMBO Molecular Medicine
Subjects:
ceramide
infertility
low BCAA diet
premature ovarian insufficiency
ROS
Online Access:https://doi.org/10.15252/emmm.202317450
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