Immune checkpoint inhibitors and cancer-related cognitive decline: a propensity score matched analysis in active chemotherapy patients

Immune checkpoint inhibitors and cancer-related cognitive decline: a propensity score matched analysis in active chemotherapy patients

BackgroundWe investigated whether 1-year trajectories of cancer-related cognitive decline (CRCD) would be different in patients with chemotherapy combined with immune checkpoint inhibitors (chemoICI group) as compared with chemotherapy alone (chemo group).MethodsParticipants scheduled with or withou...

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Main Authors: Guangmin Jian, Jiling Zeng, Jun Lu, Weidong Wang, Yongluo Jiang, Tong Huang, Yu Si Niu, Zhoufang Chai, Xin Qi, Nianqi Liu, Youlong Wang, Cantong Liu, Jiacai Lin, Guanqing Zhong, Yiming Li, Pengfei Zhu, Zong-qing Zheng, Fadian Ding, Xinjia Wang, Weizhi Liu, Ao Zhang, Yifei Ma
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Immunology
Subjects:
immune checkpoint inhibitors
cognitive dysfunction
chemotherapy
immune-related adverse events
long-term trajectory
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1540442/full
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