Molecular clustering on ctDNA improves the prognostic stratification of patients with DLBCL compared with ctDNA levels

Molecular clustering on ctDNA improves the prognostic stratification of patients with DLBCL compared with ctDNA levels

Abstract: Circulating tumor DNA (ctDNA) levels can help predict outcomes in diffuse large B-cell lymphoma (DLBCL), but its integration with DLBCL molecular clusters remains unexplored. Using the LymphGen tool in 77 DLBCL cases with both ctDNA and tissue biopsy, a 95.8% concordance rate in molecular...

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Main Authors: Riccardo Moia, Donatella Talotta, Lodovico Terzi Di Bergamo, Mohammad Almasri, Riccardo Dondolin, Matin Salehi, Chiara Cosentino, Roberta Soscia, Irene Della Starza, Alessio Bruscaggin, Annalisa Andorno, Francesca Mercalli, Stefania Cresta, Riccardo Bomben, Tamara Bittolo, Filippo Vit, Pietro Bulian, Antonella Zucchetto, Riccardo Bruna, Giulia Maria Rivolta, Mattia Schipani, Eleonora Secomandi, Sreekar Kogila, Matteo Bellia, Samir Mouhssine, Jana Nabki, Bashar Al Deeban, Joseph Ghanej, Luca Cividini, Nawar Maher, Federica Melle, Giovanna Motta, Monica Leutner, Angela Lorenzi, Abdurraouf Mokhtar Mahmoud, Wael Al Essa, Clara Deambrogi, Silvia Rasi, Luigi Petrucci, Renzo Luciano Boldorini, Alice Di Rocco, Ilaria Del Giudice, Michele Spina, Stefano Palazzolo, Fabio Canal, Vincenzo Canzonieri, Maurizio Martelli, Stefano Pileri, Valter Gattei, Robin Foà, Davide Rossi, Gianluca Gaidano
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:Blood Advances
Online Access:http://www.sciencedirect.com/science/article/pii/S2473952925000382
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