The multifaceted functions of SPC25 in cancer: from molecular pathways to targeted therapy

Spindle Pole Body Component 25 (SPC25), a critical component of the NDC80 kinetochore complex, plays an essential role in maintaining chromosomal stability during mitosis. Recent studies have revealed its aberrant expression in various cancers, highlighting its potential as both a diagnostic biomark...

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Bibliographic Details
Main Authors: Yigang Jin, Minjie Chen, Fei Chen, Zhaofeng Gao, Xiaoping Li, Lingyu Hu, Dandan Cai, Siqi Zhao, Zhengwei Song
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Medicine
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Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2025.1550901/full
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