Melanopsin Regulates Both Sleep-Promoting and Arousal-Promoting Responses to Light.

Melanopsin Regulates Both Sleep-Promoting and Arousal-Promoting Responses to Light.

Light plays a critical role in the regulation of numerous aspects of physiology and behaviour, including the entrainment of circadian rhythms and the regulation of sleep. These responses involve melanopsin (OPN4)-expressing photosensitive retinal ganglion cells (pRGCs) in addition to rods and cones....

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Main Authors: Violetta Pilorz, Shu K E Tam, Steven Hughes, Carina A Pothecary, Aarti Jagannath, Mark W Hankins, David M Bannerman, Stafford L Lightman, Vladyslav V Vyazovskiy, Patrick M Nolan, Russell G Foster, Stuart N Peirson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-06-01
Series:PLoS Biology
Online Access:https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.1002482&type=printable
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