Long-term effects of linear versus macrocyclic GBCAs on gene expression in the central nervous system of mice

Long-term effects of linear versus macrocyclic GBCAs on gene expression in the central nervous system of mice

Abstract Background We examined chronic gadolinium retention impact on gene expression in the mouse central nervous system (CNS) after injection of linear or macrocyclic gadolinium-based contrast agents (GBCAs). Methods From 05/2022 to 07/2023, 36 female mice underwent weekly intraperitoneal injecti...

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Bibliographic Details
Main Authors: Chuanbing Wang, Yuxia Tang, Jiajia Tang, Jie Zhang, Siqi Wang, Feiyun Wu, Shouju Wang
Format: Article
Language:English
Published: SpringerOpen 2025-01-01
Series:European Radiology Experimental
Subjects:
Animals
Central nervous system
Contrast media
Gadolinium
Gene expression
Online Access:https://doi.org/10.1186/s41747-024-00546-x
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https://doi.org/10.1186/s41747-024-00546-x

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