Migrasome Marker Epidermal Growth Factor Domain-Specific <i>O</i>-GlcNAc Transferase: Pan-Cancer Angiogenesis Biomarker and the Potential Role of circ_0058189/miR-130a-3p/EOGT Axis in Hepatocellular Carcinoma Progression and Sorafenib Resistance

Migrasome Marker Epidermal Growth Factor Domain-Specific <i>O</i>-GlcNAc Transferase: Pan-Cancer Angiogenesis Biomarker and the Potential Role of circ_0058189/miR-130a-3p/EOGT Axis in Hepatocellular Carcinoma Progression and Sorafenib Resistance

<b>Background</b>: The EGF domain-specific O-GlcNAc transferase (EOGT), a migrasome marker, plays emerging roles in cancer biology through O-GlcNAcylation modifications, yet its pan-cancer functions and therapeutic implications remain underexplored. This study aimed to systematically cha...

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Bibliographic Details
Main Authors: Zhe Yu, Jing Luo, Wen An, Herui Wei, Mengqi Li, Lingling He, Fan Xiao, Hongshan Wei
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Biomedicines
Subjects:
pan-cancer analysis
<i>O</i>-GlcNAcylation
hepatocellular carcinoma
EOGT
angiogenesis
biomarker
Online Access:https://www.mdpi.com/2227-9059/13/4/773
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