Atypical Clinical and Diagnostic Features in Ménétrier's Disease in a Child
Ménétrier's disease is one of the rarest protein-losing gastropathies in childhood. It is characterized clinically by non-specific gastrointestinal symptoms and edema, biochemically by hypoalbuminemia, and pathologically by enlarged gastric folds. In adults, this disease can be devastating with...
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Case Reports in Gastrointestinal Medicine |
| Online Access: | http://dx.doi.org/10.1155/2011/480610 |
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| author | Michael Chung Jaime Pittenger Deborah Flomenhoft Jeffrey Bennett Eun-Young Lee Harohalli Shashidhar |
| author_facet | Michael Chung Jaime Pittenger Deborah Flomenhoft Jeffrey Bennett Eun-Young Lee Harohalli Shashidhar |
| author_sort | Michael Chung |
| collection | DOAJ |
| description | Ménétrier's disease is one of the rarest protein-losing gastropathies in childhood. It is characterized clinically by non-specific gastrointestinal symptoms and edema, biochemically by hypoalbuminemia, and pathologically by enlarged gastric folds. In adults, this disease can be devastating with significant morbidity and mortality. In childhood, it is a self-limiting, transient and benign illness. Its treatment is largely supportive with total parenteral nutrition (TPN) while oral intake is encouraged. Acute onset of vomiting in healthy school age children can be initially explained by acute viral gastroenteritis. However, persistent vomiting associated with hematemesis and severe abdominal pain should warrant further work-up. This case report illustrates a self-limiting and rare cause of protein-losing enteropathy called Ménétrier's disease that presented with several variant clinical features not typically described in association with this entity. |
| format | Article |
| id | doaj-art-8da5e58598d541b48e96cb144fe7a4bb |
| institution | Kabale University |
| issn | 2090-6528 2090-6536 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Gastrointestinal Medicine |
| spelling | doaj-art-8da5e58598d541b48e96cb144fe7a4bb2025-02-03T01:02:19ZengWileyCase Reports in Gastrointestinal Medicine2090-65282090-65362011-01-01201110.1155/2011/480610480610Atypical Clinical and Diagnostic Features in Ménétrier's Disease in a ChildMichael Chung0Jaime Pittenger1Deborah Flomenhoft2Jeffrey Bennett3Eun-Young Lee4Harohalli Shashidhar5University of Kentucky College of Medicine, 138 Leader Avenue, Lexington, KY 40506-9983, USAUniversity of Kentucky Children's Hospital, 800 Rose Street, Lexington, KY 40536-0298, USADepartment of Pediatrics, Kentucky Clinic, J445 740 S. Limestone, Lexington, KY 40536-0284, USAUniversity of Kentucky Children's Hospital, 800 Rose Street, Lexington, KY 40536-0298, USADepartment of Pathology, Medical Science Building, MS117, 800 Rose St., Lexington, KY 40536-0298, USADivision of Pediatric Gastroenterology and Nutrition, Department of Pediatrics, University of Kentucky College of Medicine, 800 Rose Street, 109, Lexington, KY 40536-0298, USAMénétrier's disease is one of the rarest protein-losing gastropathies in childhood. It is characterized clinically by non-specific gastrointestinal symptoms and edema, biochemically by hypoalbuminemia, and pathologically by enlarged gastric folds. In adults, this disease can be devastating with significant morbidity and mortality. In childhood, it is a self-limiting, transient and benign illness. Its treatment is largely supportive with total parenteral nutrition (TPN) while oral intake is encouraged. Acute onset of vomiting in healthy school age children can be initially explained by acute viral gastroenteritis. However, persistent vomiting associated with hematemesis and severe abdominal pain should warrant further work-up. This case report illustrates a self-limiting and rare cause of protein-losing enteropathy called Ménétrier's disease that presented with several variant clinical features not typically described in association with this entity.http://dx.doi.org/10.1155/2011/480610 |
| spellingShingle | Michael Chung Jaime Pittenger Deborah Flomenhoft Jeffrey Bennett Eun-Young Lee Harohalli Shashidhar Atypical Clinical and Diagnostic Features in Ménétrier's Disease in a Child Case Reports in Gastrointestinal Medicine |
| title | Atypical Clinical and Diagnostic Features in Ménétrier's Disease in a Child |
| title_full | Atypical Clinical and Diagnostic Features in Ménétrier's Disease in a Child |
| title_fullStr | Atypical Clinical and Diagnostic Features in Ménétrier's Disease in a Child |
| title_full_unstemmed | Atypical Clinical and Diagnostic Features in Ménétrier's Disease in a Child |
| title_short | Atypical Clinical and Diagnostic Features in Ménétrier's Disease in a Child |
| title_sort | atypical clinical and diagnostic features in menetrier s disease in a child |
| url | http://dx.doi.org/10.1155/2011/480610 |
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