Norcantharidin induces G2/M arrest and apoptosis via activation of ERK and JNK, but not p38 signaling in human renal cell carcinoma ACHN cells

Renal cell carcinoma (RCC) is generally acknowledged as the most resistant primary malignancy unresponsive to conventional radiotherapy and chemotherapy treatments. Norcantharidin (NCTD), a therapeutic compound derived from medicinal plants, has been shown to trigger apoptosis, as well as antimetast...

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Bibliographic Details
Main Authors: Huang Shuaishuai, Tuergong Gulimire, Zhu Hangjie, Wang Xue, Weng Guobin, Ren Yu
Format: Article
Language:English
Published: Sciendo 2021-06-01
Series:Acta Pharmaceutica
Subjects:
Online Access:https://doi.org/10.2478/acph-2021-0012
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